G16

Guiding Inspiratory Flow: Development of the In-Check DIAL G16, a Tool for Improving Inhaler Technique

Portable inhalers are divisible into those that deliver medication by patient triggering (pMDIs: a gentle slow inhalation) and those that use the patient's inspiratory effort as the force for deaggregation and delivery (DPIs: a stronger deeper inspiratory effort). Patient confusion and poor technique are commonplace. The use of training tools has become standard practice, and unique amongst the...

Functional interaction between TAS2R receptors and G-protein alpha subunits expressed in taste receptor cells.

Bitter taste perception is a conserved chemical sense against the ingestion of poisonous substances in mammals. It could be mediated by G protein-coupled receptors that need the appropriate G proteins to transduce the signals. TAS2R receptors and a G protein α subunit, α–gustducin are believed to be key molecules for its perception (Margolskee, 2002; Montmayeur and Matsunami, 2002), but little ...

Functional interaction between T2R taste receptors and G-protein alpha subunits expressed in taste receptor cells.

Bitter taste perception is a conserved chemical sense against the ingestion of poisonous substances in mammals. A multigene family of G-protein-coupled receptors, T2R (so-called TAS2R or TRB) receptors and a G-protein alpha subunit (Galpha), gustducin, are believed to be key molecules for its perception, but little is known about the molecular basis for its interaction. Here, we use a heterolog...

Diversity in Indian equine rotaviruses: Identification of G10, P6[1] and G1 type and a new VP7 genotype (G16) strains in diarrheic foals in India

Purified Phospholipase C Isozymes by G-Protein {alpha} Subunits Purification and Characterization of Recombinant G16{alpha} From Sf9 Cells: Activation of T Kozasa,

A cDNA encoding Gi6a, the a subunit of a heterotrimeric guani nucleotide-binding protein, was expressed in Sf9 ceUls using recombinant baculovirus. G16a in membrane extracts of Sf9 ceUs activated phospholipase C-.81 (PLC-p81) in the presence of guanosine 5'-[Vthio]triphosphate; the system could not be activated by A13+, Mg2+, and F-. The Gi6a in the cYtosolic fraction of Sf9 ceHs did not stimul...